Histamine Sampling Tool
(Version 1.0)


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Design a Plan

This tool will attempt to find sampling plans which meet user-defined objectives.
The tool will search for combinations of the number of samples, n, and a concentration threshold, m, that achieve these objectives.
 
Default values are provided for the different parameters listed below. You can modify these default values to match your requirements and click on "Compute Results" to view the designed plans.

Parameter

Value

Allowable
Range

Description

Histamine Limit (H) (mg/kg):     (10 to 500) This is a user-defined maximum acceptable concentration, often a health-based and/or regulatory limit.
Level of Protection: 1 in     (100 to 1,000,000) This is the maximum acceptable fraction of samples from a lot allowed to exceed the histamine concentration limit (H). E.g. 1 in 10,000 samples.
Confidence Limit (%):     (20 to 99) This is the desired confidence limit that lots that do not meet the level of protection specified will be rejected by the sampling plan.
 
Standard Deviation (log10):     (0.1 to 2.0) This is the expected standard deviation of the histamine concentration within a lot. It is on the log10 scale. When combined with a log10 mg/kg mean concentration value, it is used to generate a log-normal distribution of histamine concentration within the lot.
Acceptable number of samples
above little m (c):
    (0 to 200,
<= nmax-1)
The plan design will include a parameter which defines a concentration threshold, m, generally referred to as "little m." Sample concentrations higher than little m are counted and compared to this value, c. If the count exceeds c then the lot is rejected.
Maximum samples (nmax) to test:     (1 to 1,000) The tool will consider plans where the number of samples, n, does not exceed nmax.
Results will be displayed below.
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